I-Palestine Academy for Science and Technology yasungulwa ngo-1994 yi-Palestine Liberation Organization ngesicelo se-UNESCO. Yasungulwa ngokusemthethweni ngeSimemezelo sikaMongameli esingunombolo 114 ngowe-1997, siqaphela isimo sayo njengenhlangano ezimele, engekho ngaphansi kukahulumeni, futhi engenzi nzuzo. Lo mthetho unikeze i-Academy amandla okusebenza njengegatsha eliyinhloko lesayensi nobuchwepheshe ezweni, elinikezwe umsebenzi wokweluleka ekwakhiweni kwezinqubomgomo, izinhlelo, namaphrojekthi okusekela intuthuko kazwelonke, nokuxhumanisa imisebenzi efanele yesayensi nezobuchwepheshe (S&T). Ngenxa yalokho, i-Academy isiphenduke isikhungo esimaphakathi nenhlangano esambulela yesayensi nobuchwepheshe ePalestine.
UDkt. Fathi Arafat wayengu eqokwe njengomongameli wayo wokuqala, no-HE Yasser Arafat, uMongameli Wesigungu Sikazwelonke SasePalestine, osebenza njengoMongameli Ohloniphekile.
Ngo-1998, uDkt. Rafiq Al-Husseini waqokwa njengoNobhala Jikelele wokuqala we-Academy. UDkt. Mohamed Ziara wamlandela njengeBamba likaNobhala Jikelele ngo-2000, kwalandela uDkt. Imad Al-Khatib ekuqaleni kuka-2001, oqale wasebenza njengeBamba likaNobhala Jikelele ngaphambi kokuba aqokwe njengoNobhala Jikelele ngasekupheleni kwalowo nyaka. UDkt. Hikmat Ajjuri uqokwe njengePhini Likamongameli Wesikole.
Isimo se-Academy siphinde saqinisekiswa ngu Isinqumo sikaMongameli No. 13 ngo-2004 (e isiZulu) , nokusisungula njengesikhungo sikazwelonke, esizimele, esizibusayo. I-Palestine Academy yeSayensi Nobuchwepheshe idlala indima ebalulekile ekuthuthukiseni isayensi, ubuchwepheshe, kanye nokusungula izinto ezintsha e-Palestine futhi iwasebenzise njengabashayeli bezomnotho, ezenhlalakahle, kanye nentuthuko yabantu. Ukuze kuzuzwe lokhu, iSikole sisebenza eduze nozakwethu abavela ezikhungweni zemfundo ephakeme, kuhulumeni, nezimboni, ngaphakathi nangaphandle. Ukudidiyela kanye nokwenza kahle imizamo kazwelonke kubaluleke kakhulu uma kubhekwa izinsiza ezilinganiselwe kanye nezinselelo ezibalulekile okubhekwe nazo. Isikhungo se-Academy siseJerusalema, sinamahhovisi engeziwe eRamallah naseGaza.
