I-ISC inamalungu nozakwethu emhlabeni wonke, futhi isebenza kuzo zonke izifunda.
Ukuze kujuliswe ukusebenzelana koMkhandlu namaLungu awo kanye nososayensi ngabanye emhlabeni wonke, i-ISC isungule izindawo eziningi ezigxile kuZifunda ezisiza ukwakha amandla ezinhlelo zesayensi kanye nezwi lesayensi emhlabeni wonke ezifundeni.
- I-Afrika: Ingxoxo yokusungula ubukhona e-Afrika Iqalile ngo-2022 nabalingani be-ISC, i-Future Africa, inhlangano yamazwe ngamazwe ase-Afrika ezinze eNingizimu Afrika, eyahlola amathuba futhi yenza izincomo eMkhandlwini ukuze uzicubungule.
- I-Asia kanye nePacific: I I-ISC Regional Focal Point yase-Asia nasePacific ibanjwe yi I-Australia Academy of Science (yethulwe ngo-2022)
- I-Asia Ephakathi neTranscaucasia: Ngo-Okthoba 2025, Amalungu e-ISC esifundeni Kunconywa ukusungula indawo okugxilwe kuyo esifundeni.
- I-Latin America kanye neCaribbean: II-SC Regional Focal Point yaseLatin America naseCaribbean ibanjwe yi I-Academia Colombiana de Ciencias Exactas, Fisicas y Naturales (yethulwe ngo-2021)
- Europe: I I-ISC European Members Group iyinhlangano ezibusayo ephethwe inhlangano engusihlalo Weqembu Labaphathi, okwamanje yi-Estonian Academy of Sciences.
- Emaphakathi Mpumalanga: I-ISC inakho isayinwe incwadi yenhloso noMnyango Wezemfundo Ephakeme, Ucwaningo kanye Nokusungula Kabusha wase-Oman ukusungula Iphoyinti Lesifunda Lokugxilwe Kuso esifundeni.